Codrituzumab - CISMeF

Preferred Label : Codrituzumab;

NCIt synonyms : Anti-Glypican 3 Monoclonal Antibody GC33;

NCIt definition : A humanized monoclonal antibody directed against the cell surface oncofetal protein glypican-3 (GPC3) with potential antineoplastic activity. Anti-GPC3 monoclonal antibody GC33 binds to GPC3 and triggers a host immune response against GPC3-expressing tumor cells, which may result in tumor cell death. GPC3, a heparin sulfate proteoglycan, is frequently upregulated in hepatocellular carcinoma and mesoderm-derived organs such as the liver, lungs, and kidney.;

UNII : U9I0PLD4HT;

CAS number : 1365267-33-9;

Molecule name : GC-33; RO 5137382; RO-5137382; RG 7686;

NCI Metathesaurus CUI : CL388379;

Details

Origin ID

C80043;

UMLS CUI

C4507381;

Automatic exact mappings (from CISMeF team)
- codrituzumab [MeSH concept]
Currated CISMeF NLP mapping
- codrituzumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- codrituzumab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Glypican-3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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