Lymphoid Enhancer-Binding Factor 1

Preferred Label : Lymphoid Enhancer-Binding Factor 1;

NCIt synonyms : TCF1-Alpha; T Cell-Specific Transcription Factor 1-Alpha; LEF-1;

NCIt definition : Lymphoid enhancer-binding factor 1 (399 aa, 44 kDa) is encoded by the human LEF1 gene. This protein is involved in Wnt signaling and transcriptional regulation.;

Details

Origin ID

C80034;

UMLS CUI

C1506866;

Currated CISMeF NLP mapping
- Lymphoid enhancer-binding factor 1 [OMIM Phenotype]
- lymphoid Enhancer-Binding factor 1 [MeSH concept]
- lymphoid enhancer-binding factor 1 [MeSH Descriptor]
OMIM relation
- Lymphoid enhancer-binding factor 1 [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- LEF1 protein, human [MeSH concept]
- LEF1 protein, human [MeSH Supplementary Concept]
- lymphoid Enhancer-Binding factor 1 [MeSH concept]
- lymphoid enhancer-binding factor 1 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LEF1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Basal Cell Carcinoma Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Pitx2 Transcription Regulation Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Chemotactic Process [NCIt concept]
- DNA Binding [NCIt concept]
- Histone Acetylation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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