NCIt synonyms : Yolk Sac Tumor of the Testis; Testicular Endodermal Sinus Tumor; Testicular Yolk Sac Neoplasm; Endodermal Sinus Tumor of the Testis; Yolk Sac Neoplasm of Testis; Yolk Sac Tumor of Testis; Endodermal Sinus Neoplasm of Testis; Endodermal Sinus Neoplasm of the Testis; Endodermal Sinus Tumor of Testis; Testicular Endodermal Sinus Neoplasm; Yolk Sac Neoplasm of the Testis;
NCIt definition : A non-seminomatous malignant germ cell tumor arising from the testis. It affects infants,
young children, and postpubertal males. It is the most frequently seen testicular
neoplasm during childhood. The vast majority of patients present with an asymptomatic
scrotal mass. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein
(AFP). It metastasizes to distant anatomic sites. Prognostic factors relate to the
clinical stage and the degree of AFP elevation.;