Azalanstat - CISMeF

Preferred Label : Azalanstat;

NCIt synonyms : 1-(((2S,4S)-4-(((p-Aminophenyl)thio)methyl)-2-(p-chlorophenethyl)-1,3-dioxolan-2-yl)methyl)imidazole;

NCIt definition : A synthetic imidazole that inhibits hepatic cholesterol biosynthesis by inhibiting the cytochrome P450 enzyme lanosterol 14alpha-demethylase. In an animal model, Azalanstat lowered serum cholesterol in a dose-depended manner.;

UNII : 2NL79NI1WS;

InChIKey : VYNIUBZKEWJOJP-UNMCSNQZSA-N;

CAS number : 143393-27-5;

Molecule name : RS-21607;

Chemical formula : C22H24ClN3O2S;

Details

Origin ID

C79817;

UMLS CUI

C0218596;

Currated CISMeF NLP mapping
- azalanstat [MeSH concept]
- azalanstat [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- azalanstat [MeSH Supplementary Concept]
- azalanstat [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Azalanstat Dihydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Azalanstat Dihydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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