NCIt definition : Human IDO1 wild-type allele is located in the vicinity of 8p11.21 and is approximately
27 kb in length. This allele, which encodes indoleamine 2,3-dioxygenase 1 protein,
plays a role in tryptophan metabolism. Expression of the gene is associated with reduction
in cellular immune responses.;
NCIt note : Aberrant expression of the INDO gene by tumor cells may be associated with resistance
to cell-mediated immunity.;