Serum Sickness

Preferred Label : Serum Sickness;

NCIt definition : Delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest pain, and dyspnea. Certain drugs (e.g., antibiotics, anticancer agents, and anti-inflammatory medications) and infectious disorders (e.g., hepatitis B) may also cause serum sickness-like reaction.;

Alternative definition : CTCAE: A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea.; NICHD: A systemic, immune complex mediated hypersensitivity reaction to injected foreign or autologous protein that usually presents four to ten days after exposure and resolves on its own. Manifestations may include fever, joint pain, rash, and swollen lymph nodes.;

Codes from synonyms : E11276;

Details

Origin ID

C79718;

UMLS CUI

C0036830;

Currated CISMeF NLP mapping
- SERUM SICKNESS [WHO-ART Preferred Term]
- Serum sickness [PASCAL descriptor]
- Serum sickness [ICD-11 More detail]
- Serum sickness [MedDRA Preferred Term]
- Transfusion reaction due to serum protein reaction (disorder) [SNOMED CT concept]
- serum sickness [Disease (Nov.)]
- serum sickness [MeSH Descriptor]
- serum sickness [MeSH concept]
- transfusion reaction due to serum protein reaction, nos [SNOMED Notion]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- SERUM SICKNESS [WHO-ART Preferred Term]
- Serum rash (disorder) [SNOMED CT concept]
- Serum reaction [MedDRA LLT]
- Serum sickness [PASCAL descriptor]
- Serum sickness [MedDRA Preferred Term]
- Transfusion reaction due to serum protein reaction (disorder) [SNOMED CT concept]
- Urticaria caused by serum (disorder) [SNOMED CT concept]
- serum sickness [Disease (Nov.)]
- serum sickness [MeSH concept]
- serum sickness [MeSH Descriptor]
- transfusion reaction due to serum protein reaction, nos [SNOMED Notion]
concept_is_in_subset
- CTCAE Adverse Events Version 4.0 Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Adverse Events Terminology [NCIt concept]
- Pediatric Adverse Events Terminology Mapped to MedDRA [NCIt concept]

Keyword's position in hierarchy(ies) :

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