Cefpirome - CISMeF

Preferred Label : Cefpirome;

NCIt synonyms : Cefpiroma; 5H-1-Pyrindinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydro-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-;

NCIt definition : A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefpirome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : S72Q2F09HY;

InChIKey : DKOQGJHPHLTOJR-WHRDSVKCSA-N;

CAS number : 84957-29-9;

Molecule name : HR 810;

Chemical formula : C22H22N6O5S2;

ChEBI ID : CHEBI:3503;

Details

Origin ID

C79563;

UMLS CUI

C0062986;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefpirome [MeSH Descriptor]
- Cefpirome [LOINC component]
- Cefpirome (substance) [SNOMED CT concept]
- Product containing cefpirome (medicinal product) [SNOMED CT concept]
- cefpirome [ATC Code]
- cefpirome [MeSH concept]
- cefpirome [SNOMED Notion]
Validated automatic mappings to BTNT
- cefpirome [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Cefpirome Sulfate [NCIt concept]
is_free_acid_or_base_form_of
- Cefpirome Sulfate [NCIt concept]

Keyword's position in hierarchy(ies) :

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