NCIt definition : The anhydrous form of cefadroxil, a semisynthetic first-generation cephalosporin with
antibacterial activity. Cefadroxil binds to and inactivates penicillin-binding proteins
(PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes
involved in the terminal stages of assembling the bacterial cell wall and in reshaping
the cell wall during growth and division. Inactivation of PBPs interferes with the
cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and
rigidity. This results in the weakening of the bacterial cell wall and causes cell
lysis.;