Preferred Label : Ambenonium Chloride Tetrahydrate;
NCIt definition : The tetrahydrate and chloride salt form of ambenonium, a bisquaternary ammonium alcohol
with parasympathomimetic activity. The positive charge of ambenonium allows it to
act as an acetylcholinesterase inhibitor by binding to the anionic site at the reactive
center of acetylcholinesterase, preventing the breakdown of acetylcholine and producing
an indirect cholinomimetic effect at both nicotinic and muscarinic receptors. Ambenonium
also has direct agonist activity at nicotinic receptors, potentiating the cholinomimetic
effect at the neuromuscular junction.;
UNII : 9T1OT01KW1;
InChIKey : FFLYNBGKFQTWPI-UHFFFAOYSA-N;
CAS number : 52022-31-8;
Chemical formula : C28H42Cl2N4O2.2Cl.4H2O;
Origin ID : C79523;
UMLS CUI : C2698080;
Semantic type(s)
concept_is_in_subset