Invasive Breast Lobular Carcinoma

Preferred Label : Invasive Breast Lobular Carcinoma;

NCIt synonyms : Classic Invasive Lobular Carcinoma; Infiltrating Lobular Carcinoma of the Breast; Infiltrating Lobular Breast Carcinoma; Infiltrating Lobular Adenocarcinoma; Invasive Lobular Carcinoma; Invasive Lobular Adenocarcinoma; Invasive Lobular Carcinoma of the Breast; Infiltrating Lobular Carcinoma of Breast; Invasive Lobular Carcinoma of Breast; Invasive Lobular Carcinoma, Classic Type;

NCIt related terms : Invasive Lobular Breast Carcinoma;

NCIt definition : An infiltrating lobular adenocarcinoma of the breast. The malignant cells lack cohesion and are arranged individually or in a linear manner (Indian files), or as narrow trabeculae within the stroma. The malignant cells are usually smaller than those of ductal carcinoma, are less pleomorphic, and have fewer mitotic figures.;

Neoplastic status : Malignant;

Details

Origin ID

C7950;

UMLS CUI

C0279565;

Automatic exact mappings (from CISMeF team)
- Lobular carcinoma of breast (disorder) [SNOMED CT concept]
- invasive lobular carcinoma [DO Concept]
Currated CISMeF NLP mapping
- Invasive lobular breast carcinoma [MedDRA Preferred Term]
- Invasive lobular carcinoma [ACR pathology]
- Invasive lobular carcinoma of breast [ICD-11 Subcategory]
- Lobular breast carcinoma invasive [MedDRA LLT]
- invasive lobular breast carcinoma [Disease (Nov.)]
Disease excludes abnormal cell
- Ductal Carcinoma Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Breast Lump [NCIt concept]
- Pain [NCIt concept]
- Single-File Linear Pattern [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Invasive lobular breast carcinoma [MedDRA Preferred Term]
- Invasive lobular carcinoma [ACR pathology]
- Invasive pleomorphic lobular carcinoma [MedDRA LLT]
- Lobular breast carcinoma invasive [MedDRA LLT]
- invasive lobular breast carcinoma [Disease (Nov.)]
Validated automatic mappings to NTBT
- Lobular carcinoma of breast (disorder) [SNOMED CT concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Cellular Population [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Lobular Carcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_associated_disease
- Breast Ductal Carcinoma In Situ and Invasive Lobular Carcinoma [NCIt concept]
- Invasive Breast Ductal Carcinoma and Invasive Lobular Carcinoma [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Terminal Ductal Lobular Unit Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Mammary Epithelium [NCIt concept]
- Terminal Ductal Lobular Unit [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]
disease_mapped_to_gene
- CDH1 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 16q [NCIt concept]
disease_may_have_molecular_abnormality
- CDH1 Gene Inactivation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
- PIK3CA Gene Mutation [NCIt concept]

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