" /> Breast Ductal Carcinoma In Situ, High Grade - CISMeF





Preferred Label : Breast Ductal Carcinoma In Situ, High Grade;

NCIt synonyms : Ductal Intraepithelial Neoplasia, Grade 3; High-Grade DCIS of Breast; High-Grade DCIS of the Breast; DCIS Grade 3; High-Grade Ductal Carcinoma In Situ of Breast; High-Grade Ductal Carcinoma In Situ of the Breast; High Grade Ductal Breast Carcinoma In Situ;

NCIt related terms : grade III ductal carcinoma in situ; DIN 3;

NCIt definition : Breast ductal carcinoma in situ characterized by the presence of neoplastic cells with severe dysplasia and the formation of micropapillary, cribriform, or solid patterns. The nuclei show marked pleomorphism and have prominent nucleoli. Mitotic activity is usually present. There is comedo-type of necrosis present in the ducts. The necrotic debris is surrounded by pleomorphic malignant cells.;

Alternative definition : NCI-GLOSS: A condition in which cells that look very different from normal cells under a microscope are found in the lining of a breast duct. There may also be areas of dead cells in the abnormal tissue. The abnormal cells have not spread outside the duct to other tissues in the breast. Grade III ductal carcinoma in situ tends to grow more quickly than grade I or grade II ductal carcinoma in situ and is more likely to come back or spread to other tissues. Also called grade III DCIS, high-grade DCIS, and high-grade ductal carcinoma in situ.;

Neoplastic status : Malignant;

ICD-O code : 8501/2;

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29/04/2024


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