Grade III Lymphomatoid Granulomatosis

Preferred Label : Grade III Lymphomatoid Granulomatosis;

NCIt synonyms : Angiocentric Immunoproliferative Lesion Grade III; Grade III Angiocentric Immunoproliferative Lesions; Grade III Angiocentric Immunoproliferative Lesion; Grade III LYG;

NCIt definition : Lymphomatoid granulomatosis characterized by the presence of aggregates of neoplastic large B-lymphocytes, usually admixed with pleomorphic and Hodgkin-like cells, in a background of chronic inflammation. Necrotic changes are present and are usually extensive. Grade III lymphomatoid granulomatosis should be approached clinically as a subtype of diffuse large B-cell lymphoma.;

Neoplastic status : Malignant;

Details

Origin ID

C7933;

UMLS CUI

C0279067;

Currated CISMeF NLP mapping
- Angiocentric immunoproliferative lesion grade 3 [MedDRA LLT]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Fever [NCIt concept]
- Fibrinoid Necrosis [NCIt concept]
- Malaise [NCIt concept]
- Musculoskeletal Pain [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Angiocentric immunoproliferative lesion grade 3 [MedDRA LLT]
concept_is_in_subset
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Hematopoietic and Lymphoid Cell [NCIt concept]
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Large B-Lymphocyte [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_associated_disease
- EBV Infection [NCIt concept]
- Infectious Disorder [NCIt concept]
- Viral Infection [NCIt concept]
disease_has_finding
- Angiocentric Pattern [NCIt concept]
- Angiodestructive Pattern [NCIt concept]
- Atypia [NCIt concept]
- Borderline Lesion [NCIt concept]
- Chronic Inflammatory Infiltrate [NCIt concept]
- Diffuse Pattern [NCIt concept]
- Epstein-Barr Virus Positive [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Monomorphic Cellular Infiltrate [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- EBV-Transformed Mature B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Mature Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_abnormal_cell
- Hodgkin-Like Cell [NCIt concept]
- Neoplastic B-Immunoblast [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]

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