" /> CD4 CD25 Regulatory T Cells - CISMeF





Preferred Label : CD4 CD25 Regulatory T Cells;

NCIt synonyms : CD4 CD25 Regulatory T Cells; CD4 CD25 FOXP3 Regulatory T Cells;

NCIt related terms : T-regulatory cell; suppressor T cell; T reg; regulatory T cell;

NCIt definition : Regulatory T cells that express CD4 and CD25 (interleukin 2 receptor) antigens, with immunomodulating activity. CD4 CD25 T regulatory cells (Tregs), a subset of CD4 T cells expressing high levels of CD25 and the transcription factor Foxp3, are essential in maintaining immunologic homeostasis, preventing autoimmunity by suppressing self-reactive T cells; CD4 CD25 Tregs may induce tolerance to allogeneic organ transplants such as hematopoetic stem cell transplants (HSCTs).;

Alternative definition : NCI-GLOSS: A type of immune cell that blocks the actions of some other types of lymphocytes, to keep the immune system from becoming over-active. T-regulatory cells are being studied in the treatment of cancer. A T-regulatory cell is a type of white blood cell and a type of lymphocyte.;

Codes from synonyms : CDR0000633899; CDR0000633903; CDR0000633904; CDR0000633901;

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10/05/2025


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