Stage III Chronic Lymphocytic Leukemia

Preferred Label : Stage III Chronic Lymphocytic Leukemia;

NCIt synonyms : Stage III CLL; Chronic Lymphocytic Leukemia Stage III; CLL Stage III; Stage III Chronic Lymphocytic Leukemia- Modified Rai Staging System;

NCIt related terms : Stage III Chronic Lymphocytic Leukemia (CLL);

NCIt definition : Risk: High; Findings: Lymphocytosis and hemoglobin less than 11 g/dL; Survival (months): 30. (from AJCC 8th Ed.);

Alternative definition : NCI-GLOSS: There are too many lymphocytes in the blood and there are too few red blood cells. The lymph nodes, liver, or spleen may be larger than normal.;

Neoplastic status : Malignant;

Codes from synonyms : CDR0000045061;

Details

Origin ID

C7876;

UMLS CUI

C0278769;

Disease excludes abnormal cell
- Leukemic Plasma Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Fatigue [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Chronic lymphocytic leukaemia stage 3 [MedDRA Preferred Term]
- Chronic lymphocytic leukemia stage 3 [MedDRA LLT]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Acute Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Leukemic Cell [NCIt concept]
- Leukemic Lymphocyte [NCIt concept]
- Leukemic Small Lymphocyte with Clumped Chromatin [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Small Lymphocyte with Clumped Chromatin [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_is_stage
- Rai Stage [NCIt concept]
- Stage III [NCIt concept]
disease_mapped_to_chromosome
- Human Chromosome 11 [NCIt concept]
- Human Chromosome 12 [NCIt concept]
- Human Chromosome 13 [NCIt concept]
- Human Chromosome 17 [NCIt concept]
- Human Chromosome 6 [NCIt concept]
disease_mapped_to_gene
- BCL3 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12q13 [NCIt concept]
- Trisomy 12 [NCIt concept]
- del(11q22q23) [NCIt concept]
- del(13q14) [NCIt concept]
- del(17p13) [NCIt concept]
- del(6q21) [NCIt concept]
pathogenesis_of_disease_involves_gene
- BCL3 Gene [NCIt concept]
- BCL3 wt Allele [NCIt concept]

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