Preferred Label : Zirconium Zr 89 Cetuximab;
NCIt synonyms : Cetuximab-Zirconium-89; Zirconium-89-Labeled Cetuximab; Cetuximab-Zr-89; Zirconium-Zr 89 Cetuximab;
NCIt definition : A radioimmunoconjugate comprised of the recombinant chimeric monoclonal antibody cetuximab
labeled with the radioisotope zirconium Zr 89 (Zr 89) with radioisotopic activity
and potential imaging use. The antibody moiety of zirconium Zr 89 cetuximab binds
to the extracellular domain of the epidermal growth factor receptor (EGFR). Upon binding,
the radioisotope moiety may be detected using positron emission tomography (PET),
allowing the imaging and quantification of EGFR-expressing tumor cells. EGFR is a
tyrosine kinase that may be overexpressed on the cell surfaces of various tumor cell
types.;
NCI Metathesaurus CUI : CL387588;
Origin ID : C78473;
UMLS CUI : C2700332;
Semantic type(s)
- concept_is_in_subset
