NCIt definition : Acute appendicitis with gangrenous changes resulting in the rupture of the appendiceal
wall. The appendiceal wall rupture causes the release of inflammatory and bacterial
contents from the appendiceal lumen into the abdominal cavity.;
Alternative definition : CTCAE: A disorder characterized by acute inflammation to the vermiform appendix caused
by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal
wall. The appendiceal wall rupture causes the release of inflammatory and bacterial
contents from the appendiceal lumen into the abdominal cavity.;