ACKR1 wt Allele

Preferred Label : ACKR1 wt Allele;

NCIt synonyms : CCBP1; DARC; FY; WBCQ1; GPD; GpFy; Dfy; CD234; Atypical Chemokine Receptor 1 (Duffy Blood Group) wt Allele; Duffy Blood Group System Gene; Duffy Blood Group, Chemokine Receptor Gene; Blood Group, Duffy System Gene; DARC wt Allele; CTA-134P22.3;

NCIt definition : Human ACKR1 wild-type allele is located within 1q21-q22 and is approximately 3 kb in length. This allele, which encodes atypical chemokine receptor 1 protein, plays a role in the mediation of cellular interactions with cytokines. Polymorphisms in the gene are the basis for the Duffy blood group types.;

NCIt note : Ensembl reports the DARC gene in the vicinity of 1q23.2.; Genetic variation of the DARC gene influences resistance to Plasmodium vivax infection.; Genetic variation of the DARC gene may play a role in HIV susceptibility.;

GenBank Accession Number : U01839;

Details

Origin ID

C78152;

UMLS CUI

C2699545;

Currated CISMeF NLP mapping
- Blood group, duffy system [OMIM Phenotype]
OMIM relation
- Blood group, duffy system [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1q21-q22 [NCIt concept]
gene_plays_role_in_process
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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