Alamifovir - CISMeF

Preferred Label : Alamifovir;

NCIt synonyms : Bis(2,2,2-trifluoroethyl) ((2-{2-amino-6-((4-methoxyphenyl)sulfanyl)-9H-purin-9-yl}ethoxy)methyl)phosphonate;

NCIt definition : A purine nucleotide analog prodrug with activity against wild-type and lamivudine-resistant hepatitis B virus (HBV). Alamifovir acts by inhibiting viral DNA priming and viral DNA packaging, thereby decreasing HBV replication.;

UNII : 0N739K2A8A;

InChIKey : VDBGPMJFHCJMOL-UHFFFAOYSA-N;

CAS number : 193681-12-8;

Molecule name : LY582563; LY 582563; MCC-478; MCC 478;

Chemical formula : C19H20F6N5O5PS;

Details

Origin ID

C77923;

UMLS CUI

C1567849;

Currated CISMeF NLP mapping
- alamifovir [MeSH concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- alamifovir [MeSH concept]
Validated automatic mappings to NTBT
- 2-amino-6-(4-methoxyphenylthio)-9-(2-(phosphonomethoxy)ethyl)purine bis(2,2,2-trifluoroethyl) ester [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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