Sapitinib - CISMeF

Preferred Label : Sapitinib;

NCIt synonyms : ErbB Kinase Inhibitor AZD8931; 2-(4-((4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-n-methylacetamide;

NCIt definition : An erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. erbB kinase inhibitor AZD8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization.;

UNII : 3499328002;

InChIKey : DFJSJLGUIXFDJP-UHFFFAOYSA-N;

CAS number : 848942-61-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 848942-61-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : AZD8931;

Chemical formula : C23H25ClFN5O3;

Details

Origin ID

C77887;

UMLS CUI

C2700009;

Automatic exact mappings (from CISMeF team)
- sapitinib [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Epidermal Growth Factor Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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