Preferred Label : Glucosamine Sulfate/Chondroitin Sulfate Tablet;
NCIt synonyms : Glucosamine Sulfate Chondroitin Sulfate Tablet;
NCIt definition : An oral tablet formulation of a dietary supplement containing the sulfate salts of
the amino sugar glucosamine and the glucosaminoglycan chondroitin with potential analgesic,
anti-inflammatory, and anti-arthritic activities. Both glucosamine and chondroitin
are naturally occurring substances that play a key role in cartilage formation and
repair. Glucosamine is an essential substrate for glycosaminoglycans and hyaluronic
acid, needed for formation of the joint proteoglycan structural matrix, and may prevent
chondrocytic catabolic activity and inhibit production of inflammatory mediators.
Chondroitin is the major glycosaminoglycan in cartilage, responsible for the elasticity
of cartilage; it may reduce the IL-1beta-induced nuclear factor-kappaB (NF-kB) translocation
in chondrocytes, inhibiting NF-kB-mediated inflammatory processes.;
NCI Metathesaurus CUI : CL387268;
Origin ID : C77881;
UMLS CUI : C2697504;
Semantic type(s)
- concept_is_in_subset
