Preferred Label : Murine TYRP2 Plasmid DNA Vaccine;
NCIt definition : A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related
protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities.
Upon administration, murine TYRP2 plasmid DNA vaccine may stimulate the host immune
system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing
TYRP2; this vaccine may also induce an immune response against tyrosinase-related
protein-1 (TYRP1). TYRP2 and TYRP1, melanosomal membrane glycoproteins upregulated
in melanoma cells, are involved in melanin synthesis.;
NCI Metathesaurus CUI : CL386969;
Origin ID : C77877;
UMLS CUI : C2698274;
Semantic type(s)
- concept_is_in_subset
