Preferred Label : Allogeneic Multipotent Adult Progenitor Cells;
NCIt synonyms : Allogeneic Human Adult Bone Marrow-Derived Progenitor Cells;
CISMeF synonym : allogeneic MAPC;
NCIt related terms : MULTIPOTENT ADULT PROGENITOR CELLS (BONE MARROW DERIVED);
NCIt definition : A biologic product that consists of undifferentiated stem cells, obtained from adult
bone marrow or other non-embryonic tissue sources, that are expanded in vitro and
deposited in master cell banks for off-the-shelf use, with potential hematopoiesis-inducing
and immunomodulating activities. Allogeneic multipotent adult progenitor cells (MAPCs)
are non-immunogenic due to the lack of major histocompatibility (MHC) molecule expression,
and so elicit no immune response upon administration. In vivo, bone marrow-derived
adult stem cells are capable of maturing into a broad range of cell types and may
help restore the immune system by producing multiple therapeutic molecules in response
to inflammation and tissue damage.;
UNII : WNR9FH307P;
Drug name : MultiStem;
NCI Metathesaurus CUI : CL383616;
Origin ID : C77874;
UMLS CUI : C2697994;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
