" /> Solitomab - CISMeF





Preferred Label : Solitomab;

NCIt synonyms : Anti-EpCAM BiTE; Anti-EpCAM Anti-CD3 Recombinant Bispecific Monoclonal Antibody MT110;

NCIt definition : A recombinant bispecific monoclonal antibody directed against both CD3 and epithelial cell adhesion molecule (EpCAM) with potential immunomodulating and antineoplastic activities. Solitomab attaches to both CD3-expressing T lymphocytes and EpCAM-expressing tumor cells, thereby selectively cross-linking tumor and T lymphocytes; this may result in the recruitment of cytotoxic T lymphocytes (CTL) to T lymphocyte/tumor cell aggregates and the CTL-mediated death of EpCAM-expressing tumor cells. CD3 is an antigen expressed on mature T cells; EpCAM, a cell surface protein, is expressed by a variety of tumor cells and is frequently found in head and neck cancers.;

UNII : ZQQ51B5708;

CAS number : 1005198-65-1;

Molecule name : MT110;

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08/05/2025


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