" /> Molgramostim - CISMeF





Preferred Label : Molgramostim;

NCIt definition : A recombinant form of human granulocyte macrophage colony stimulating factor (GM-CSF), with potential immunostimulating activity. Upon administration as inhalation solution via nebulizer, molgramostim binds to specific cell surface receptors and promotes or restores GM-CSF signaling, thereby modulating the proliferation and differentiation of a variety of hematopoietic progenitor cells with some specificity towards stimulation of leukocyte production. This agent also activates neutrophils, monocytes, macrophages, and dendritic cells and promotes antigen presentation, upregulates antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin (IL)-2-mediated, lymphokine-activated killer cell function. In addition, the restoration of GM-CSF signaling promotes surfactant clearing by pulmonary alveolar macrophages.;

UNII : B321AL142J;

CAS number : 99283-10-0;

Drug name : Macrogen; Leucomax; Molgradex;

Molecule name : Sch 39300;

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29/07/2025


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