Ispinesib Mesylate

Preferred Label : Ispinesib Mesylate;

NCIt definition : The mesylate salt form of ispinesib, a synthetic small molecule, derived from quinazolinone, and kinesin spindle protein (KSP) inhibitor, with antineoplastic activity. Ispinesib selectively inhibits KSP and prevents its binding to microtubules, resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the M-phase, and cell death in tumor cells that are actively dividing.;

UNII : R6ZMD4UH3D;

InChIKey : MRKSDPIHUJSKRA-HZPIKELBSA-N;

CAS number : 514820-03-2;

Chemical formula : C30H33ClN4O2.CH4O3S;

Détails

Origin ID

C77518;

UMLS CUI

C2697824;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Ispinesib [NCIt concept]
is_salt_form_of
- Ispinesib [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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