NCIt definition : A condition in which plasma cells secrete immunoglobulin light chains of only one
type, kappa or lambda. Light chain deposition disease is often associated with multiple
myeloma or lymphoproliferative disease, but as many as 50% of patients have no evidence
of neoplastic plasma cell proliferation. Light chains excreted in the urine are known
as Bence Jones protein. Amyloidosis and severe renal failure occur more frequently
than in multiple myeloma. Also known as Bence Jones myeloma. L-chain disease, L-chain
myeloma, and LCDD.;