Light Chain Deposition Disease

Preferred Label : Light Chain Deposition Disease;

NCIt synonyms : Bence Jones Myeloma; Light Chain Disease; Light Chain Gammopathy;

NCIt definition : A condition in which plasma cells secrete immunoglobulin light chains of only one type, kappa or lambda. Light chain deposition disease is often associated with multiple myeloma or lymphoproliferative disease, but as many as 50% of patients have no evidence of neoplastic plasma cell proliferation. Light chains excreted in the urine are known as Bence Jones protein. Amyloidosis and severe renal failure occur more frequently than in multiple myeloma. Also known as Bence Jones myeloma. L-chain disease, L-chain myeloma, and LCDD.;

Neoplastic status : Undetermined;

Détails

Origin ID

C7727;

UMLS CUI

C0238239;

Currated CISMeF NLP mapping
- Light chain deposition disease [ICD-11 Sub-sub category]
- Light chain deposition disease [ORDO Disease]
- Light chain deposition disease (disorder) [SNOMED CT concept]
- Light chain disease [MedDRA Preferred Term]
- Light chain disease (disorder) [SNOMED CT concept]
- light chain disease, nos [SNOMED Notion]
- light chain myeloma [Disease (Nov.)]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Microaneurysm [NCIt concept]
- Monoclonal Gammopathy [NCIt concept]
- Neoplastic Plasma Cells Present in Bone Marrow [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
See also inter- (CISMeF)
- Light chain myeloma (disorder) [SNOMED CT concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Light chain deposition disease [ORDO Disease]
- Light chain deposition disease [ICD-11 Sub-sub category]
- Light chain deposition disease (disorder) [SNOMED CT concept]
- Light chain disease [MedDRA Preferred Term]
- Light chain disease (disorder) [SNOMED CT concept]
- light chain disease, nos [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_finding
- Amyloid Deposition [NCIt concept]
- Apple Green Dichromism Present in Polarized Congo-Red Stained Sections [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Immunoglobulin Heavy Chain Deposition [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Immunoglobulin Deposition [NCIt concept]
- Immunoglobulin Light Chain Deposition [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Arthritis [NCIt concept]
- Coagulation Disorder [NCIt concept]
- Congestive Heart Failure [NCIt concept]
- Monoclonal Gammopathy of Undetermined Significance [NCIt concept]
- Multiple Myeloma [NCIt concept]
- Nephrotic Syndrome [NCIt concept]
- Renal Failure [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients