IDH1 wt Allele

Preferred Label : IDH1 wt Allele;

NCIt synonyms : PICD; IDP; IDH; Isocitrate Dehydrogenase 1 (NADP ), Soluble wt Allele; IDPC; IDCD; HEL-216; HEL-S-26;

NCIt definition : The IDH1 wt Allele is located in the vicinity of 2q33.3 and is approximately 19 kb in length. This allele, which encodes isocitrate dehydrogenase [NADP] cytoplasmic protein, plays a role in carbohydrate metabolism.;

NCIt note : Mutation of the IDH1 gene has been linked to increased occurrence of glioblastoma.;

GenBank Accession Number : NM_005896;

Details

Origin ID

C77216;

UMLS CUI

C2697642;

OMIM relation
- Isocitrate dehydrogenase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Glioblastoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Anaplastic Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted [NCIt concept]
- Astrocytoma, IDH-Mutant [NCIt concept]
- Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted [NCIt concept]
gene_is_element_in_pathway
- Citrate Cycle (TCA Cycle) Pathway [NCIt concept]
gene_plays_role_in_process
- Carbohydrate Metabolic Process [NCIt concept]
- Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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