Preferred Label : Cefprozil, (E)-;
NCIt synonyms : Cefprozil, E-Isomer; Cefprozil E-Isomer;
NCIt definition : An E-isomer of a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal
activity. Cefprozil's effect is dependent on its binding to penicillin-binding proteins
(PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition
of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine
bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis
of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell
wall synthesis formation.;
UNII : 3ADV90MJVU;
InChIKey : ALYUMNAHLSSTOU-CIRGZYLNSA-N;
CAS number : 111900-24-4;
Chemical formula : C18H19N3O5S.H2O;
Origin ID : C77189;
UMLS CUI : C2699146;
Semantic type(s)
- concept_is_in_subset
