Preferred Label : Cefprozil Anhydrous, (E)-;
NCIt synonyms : Cefprozil Anhydrous, E-Isomer; Cefprozil Anhydrous E-Isomer;
NCIt definition : An anhydrous E-isomer of a semi-synthetic cephalosporin and a beta-lactam antibiotic
with bactericidal activity. Cefprozil's effect is dependent on its binding to penicillin-binding
proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in
the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of
the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting
consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial
septum and cell wall synthesis formation.;
UNII : S1SDI2FJIY;
InChIKey : WDLWHQDACQUCJR-ZAMMOSSLSA-N;
CAS number : 92676-86-3;
Chemical formula : C18H19N3O5S;
Origin ID : C77188;
UMLS CUI : C2699144;
Semantic type(s)
- concept_is_in_subset
