CHRNA5 wt Allele

Preferred Label : CHRNA5 wt Allele;

NCIt synonyms : Neuronal Nicotinic Acetylcholine Receptor, Alpha5 Subunit Gene; NACHRA5; LNCR2; Cholinergic Receptor, Nicotinic, Alpha Polypeptide 5 Gene; Cholinergic Receptor, Nicotinic, Alpha 5 (Neuronal) wt Allele; Acetylcholine Receptor, Nicotinic, Alpha 5 (Neuronal) Gene; Cholinergic Receptor, Nicotinic, Alpha 5 Gene; Acetylcholine Receptor, Neuronal Nicotinic, Alpha-5 Subunit Gene;

NCIt definition : Human CHRNA5 wild-type allele is located in the vicinity of 15q24 and is approximately 29 kb in length. This allele, which encodes neuronal acetylcholine receptor subunit alpha-5 protein, is involved in the mediation of ion transport. Mutation of the gene is associated with lung cancer type 2.;

GenBank Accession Number : NM_000745;

Details

Origin ID

C77123;

UMLS CUI

C2698729;

OMIM relation
- Cholinergic receptor, neuronal nicotinic, alpha polypeptide 5 [OMIM gene]
See also inter- (CISMeF)
- Smoking as a quantitative trait locus 3 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Lung Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 15q24 [NCIt concept]
gene_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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