Uveal Melanoma

Preferred Label : Uveal Melanoma;

NCIt synonyms : UVM; Uveal Tract Melanoma;

NCIt related terms : MELANOMA, UVEAL, MALIGNANT; Intraocular Melanoma; Melanoma of Uvea; Melanoma of the Uvea;

NCIt definition : A melanoma derived from melanocytes of the uveal tract. It is the most common primary intraocular tumor in the United States and Western Europe. Similar to melanoma of the skin, it is rare in Africa and Asia. Diagnostic procedures include ophthalmoscopic exam, fluorescein angiography and ultrasound. Treatment includes: surgical excision of the eye, iridocyclectomy and tumor resection. Recent treatments also include radiotherapy or photo coagulation. Classification of uveal melanomas recognizes four cell types within these tumors: epithelioid, intermediate, mixed cell, and spindle cell types. The spindle cell type uveal melanomas are further sub-classified as spindle cell type A and spindle cell type B.;

Alternative definition : CDISC: A malignant neoplasm of the uvea composed of melanocytes.; NCI-GLOSS: A rare cancer of melanocytes (cells that produce the pigment melanin) found in the eye.;

Neoplastic status : Malignant;

Codes from synonyms : CDR0000269460;

Details

Origin ID

C7712;

UMLS CUI

C0220633;

Currated CISMeF NLP mapping
- Intraocular melanoma [MedDRA Preferred Term]
- Intraocular melanoma [MedDRA LLT]
- Melanoma of uvea [ICD-11 More detail]
- Melanoma, uveal [OMIM Phenotype]
- Uveal Melanoma [MeSH Descriptor]
- Uveal malignant melanoma [PASCAL descriptor]
- Uveal melanoma [MedDRA Preferred Term]
- Uveal melanoma [MeSH concept]
- Uveal melanoma [HPO term]
- Uveal melanoma [ORDO Disease]
- intraocular melanoma [Disease (Nov.)]
- uveal melanoma [DO Concept]
- uveal melanoma [MeSH Supplementary Concept]
DO Cross reference
- uveal melanoma [DO Concept]
Disease may have findings
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
Excludes anatomical site(s)
- Skin [NCIt concept]
Has associated anatomic sites
- Eye [NCIt concept]
- Uvea [NCIt concept]
Manual NTBT mappings (CISMeF)
- Intraocular melanoma NOS [MedDRA LLT]
- eye cancer [MedlinePlus Topic]
- melanoma [MedlinePlus Topic]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Intraocular melanoma [MedDRA LLT]
- Intraocular melanoma [MedDRA Preferred Term]
- Intraocular melanoma NOS [MedDRA LLT]
- Melanoma, uveal [OMIM Phenotype]
- Uveal Melanoma [MeSH Descriptor]
- Uveal melanoma [ORDO Disease]
- Uveal melanoma [MeSH concept]
- Uveal melanoma [HPO term]
- Uveal melanoma [MedDRA Preferred Term]
- intraocular melanoma [Disease (Nov.)]
- uveal melanoma [MeSH Supplementary Concept]
- uveal melanoma [DO Concept]
Validated automatic mappings to NTBT
- ocular melanoma [DO Concept]
concept_is_in_subset
- CDISC SEND Terminology [NCIt concept]
- CDISC SEND Tumor Findings Results Terminology [NCIt concept]
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Melanoma Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_primary_anatomic_site
- Eye [NCIt concept]
- Uvea [NCIt concept]
disease_mapped_to_gene
- BAP1 Gene [NCIt concept]
- GNA11 Gene [NCIt concept]
- GNAQ Gene [NCIt concept]
disease_may_have_molecular_abnormality
- BAP1 Gene Mutation [NCIt concept]
- CYSLTR2 Gene Mutation [NCIt concept]
- EIF1AX Gene Mutation [NCIt concept]
- GNA11 Gene Mutation [NCIt concept]
- GNAQ Gene Mutation [NCIt concept]
- PLCB4 Gene Mutation [NCIt concept]
- SF3B1 Gene Mutation [NCIt concept]
may_be_associated_disease_of_disease
- BAP1 Tumor Predisposition Syndrome [NCIt concept]
pathogenesis_of_disease_involves_gene
- BAP1 Gene [NCIt concept]
- BAP1 wt Allele [NCIt concept]
- GNA11 Gene [NCIt concept]
- GNA11 wt Allele [NCIt concept]
- GNAQ Gene [NCIt concept]
- GNAQ wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients