Preferred Label : CF-1 Mouse;
NCIt synonyms : CF-1;
NCIt related terms : CF1;
NCIt definition : Thought to be wild albino in origin, this strain was obtained by Carworth farms from
a Missouri laboratory. It was intensely inbred by N. Goto in 1978 from a single Carworth
pair, the progeny of which is used today. The CF-1 mouse has an albino coat with genotype
c and is used as a multi-purpose strain for a variety of applications including infectious
disease modeling, embryological studies, and safety and efficacy testing. In this
mouse model, cleft palate formation can be induced by cortisone while alloxan treatment
induces diabetes in a high percentage of CF-1 mice.;
Alternative definition : CDISC: Thought to be wild albino in origin, this strain was obtained by Carworth farms
from a Missouri laboratory. It was intensely inbred by N. Goto in 1978 from a single
Carworth pair, the progeny of which is used today. The CF-1 mouse has an albino coat
with genotype c.;
Origin ID : C77116;
UMLS CUI : C2698722;
Automatic exact mappings (from CISMeF team)
Semantic type(s)
concept_is_in_subset