NCIt definition : A third generation, synthetic, water-soluble, pentapeptide analog of the marine depsipeptide
dolastatin 15, with potential antimitotic and antineoplastic activities. Tasidotin
and its metabolite, tasidotin C-carboxylate, suppress the dynamic instability behavior
of the microtubules through a reduction of the shortening rate (disassembly); reduction
of the switching frequency from growth to shortening; and by reducing microtubules
growth time. This may eventually result in a reduction of cell growth.;
UNII : 05G07285DK;
InChIKey : QMCOCIWNMHBIIA-LROMGURASA-N;
CAS number : 192658-64-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 192658-64-3
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