Preferred Label : Prednimustine;
NCIt synonyms : Chlorambucil Prednisolone Ester; Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-,21-(4-(p-(bis(2-chloroethyl)amino)phenyl)butyrate); 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-[4-[p-[bis(3-chloroethyl)amino]phenyl]butyrate]; 11beta-21-[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]-11,17-dihydroxypregna-1,4-diene-3,20-dione;
NCIt related terms : Leo 1031; Sterecyt;
NCIt definition : The prednisolone ester of chlorambucil and nitrogen mustard alkylating agent with
antineoplastic activity. Prednimustine itself is not cytotoxic, however, it becomes
cytotoxic upon hydrolysis by serum esterases to chlorambucil. Therefore, the increased
potency of prednimustine is linked to the prolonged availability of free chlorambucil.;
UNII : 9403SIO2S8;
InChIKey : HFVNWDWLWUCIHC-GUPDPFMOSA-N;
CAS number : 29069-24-7;
Drug name : Sterecyt; Stereocyt;
Molecule name : LEO-1031;
Chemical formula : C35H45Cl2NO6;
NSC code : 134087; 171345;
Codes from synonyms : NSC0171345; 76031;
Origin ID : C768;
UMLS CUI : C0032949;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
