" /> Prednimustine - CISMeF





Preferred Label : Prednimustine;

NCIt synonyms : Chlorambucil Prednisolone Ester; Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-,21-(4-(p-(bis(2-chloroethyl)amino)phenyl)butyrate); 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-[4-[p-[bis(3-chloroethyl)amino]phenyl]butyrate]; 11beta-21-[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]-11,17-dihydroxypregna-1,4-diene-3,20-dione;

NCIt related terms : Leo 1031; Sterecyt;

NCIt definition : The prednisolone ester of chlorambucil and nitrogen mustard alkylating agent with antineoplastic activity. Prednimustine itself is not cytotoxic, however, it becomes cytotoxic upon hydrolysis by serum esterases to chlorambucil. Therefore, the increased potency of prednimustine is linked to the prolonged availability of free chlorambucil.;

UNII : 9403SIO2S8;

InChIKey : HFVNWDWLWUCIHC-GUPDPFMOSA-N;

CAS number : 29069-24-7;

Drug name : Sterecyt; Stereocyt;

Molecule name : LEO-1031;

Chemical formula : C35H45Cl2NO6;

NSC code : 134087; 171345;

Codes from synonyms : NSC0171345; 76031;

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30/07/2025


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