NCIt related terms : Adamantinoma of long bones; ADAMANTINOMA, MALIGNANT;
NCIt definition : A low grade malignant neoplasm arising from the long bones. The tibia is the most
frequently affected bone site. Patients present with swelling which may or may not
be associated with pain. Morphologically, it is characterized by a biphasic pattern
consisting of an epithelial and an osteofibrous component. The vast majority of cases
recur if they are not treated with radical surgery. In a minority of cases the tumor
may metastasize to other anatomic sites including lymph nodes, lungs, liver, brain,
and skeleton.;
Alternative definition : CDISC: A low-grade malignant neoplasm composed of epithelial cells and a spindle cell
osteo-fibrous proliferation.;