NCIt related terms : Fluorine F 18 Sodium Fluoride;
NCIt definition : A radiopharmaceutical consisting of the sodium salt of fluorine F 18 fluoride with
radioisotopic and bone mineralizing activities. Fluoride binds to calcium ions in
hydroxyapatite crystals in bone. The uptake and incorporation of positron-emitting
fluorine F 18 fluoride into bone can be imaged using positron emission tomography
(PET) or single-photon emission computed tomography (SPECT), allowing visualization
of malignant bone lesions in which regional blood flow and bone turnover are increased.;