Preferred Label : Nafcillin Sodium Anhydrous;
NCIt definition : The anhydrous form of the sodium salt of nafcillin, a narrow-spectrum beta-lactamase-resistant
penicillin with antibacterial activity. Nafcillin binds to and inactivates penicillin-binding
proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation
of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial
cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and
results in the weakening of the bacterial cell wall, eventually causing cell lysis.;
UNII : SY07234TTS;
InChIKey : AYAPZOUDXCDGIF-FRFVDRIFSA-M;
CAS number : 985-16-0;
Chemical formula : C21H21N2O5S.Na;
ChEBI ID : CHEBI:7448;
Origin ID : C76224;
UMLS CUI : C2698426;
Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
