Preferred Label : Azithromycin Monohydrate;
NCIt definition : The monohydrate form of azithromycin, an orally bioavailable azalide derived from
erythromycin, and a member of a subclass of macrolide antibiotics, with anti-bacterial
activity. Upon oral administration, azithromycin reversibly binds to the 23S rRNA
of the 50S ribosomal subunit of the bacterial ribosome of susceptible microorganisms,
thereby inhibiting the translocation step of protein synthesis by preventing the assembly
of the 50S ribosomal subunit. This inhibits bacterial protein synthesis, inhibits
cell growth and causes cell death.;
UNII : JTE4MNN1MD;
InChIKey : HQUPLSLYZHKKQT-WVVFQGGUSA-N;
CAS number : 121470-24-4;
Chemical formula : C38H72N2O12.H2O;
Origin ID : C76215;
UMLS CUI : C0886592;
Semantic type(s)
- Validated automatic mappings to NTBT
- concept_is_in_subset
