Cefpimizole - CISMeF

Preferred Label : Cefpimizole;

NCIt definition : A semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefpimizole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 24S58UHU7N;

InChIKey : LNZMRLHZGOBKAN-KAWPREARSA-N;

CAS number : 84880-03-5;

Chemical formula : C28H26N6O10S2;

Details

Origin ID

C76173;

UMLS CUI

C0055009;

Currated CISMeF NLP mapping
- Cefpimizole [ICD-11 Extension code]
- Cefpimizole [ICHI extension code]
- Cefpimizole [SMS substance]
- cefpimizole [MeSH Supplementary Concept]
- cefpimizole [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefpimizole [ICD-11 Extension code]
- cefpimizole [MeSH Supplementary Concept]
- cefpimizole [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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