Cefozopran - CISMeF

Preferred Label : Cefozopran;

NCIt definition : A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefozopran binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 1LG87K28LW;

InChIKey : QDUIJCOKQCCXQY-WHJQOFBOSA-N;

CAS number : 113359-04-9;

Chemical formula : C19H17N9O5S2;

Details

Origin ID

C76172;

UMLS CUI

C0246584;

Currated CISMeF NLP mapping
- Cefozopran [ICD-11 Extension code]
- Cefozopran [MeSH Descriptor]
- Cefozopran [SMS substance]
- Cefozopran [LOINC component]
- cefozopran [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefozopran [MeSH Descriptor]
- Cefozopran [LOINC component]
- cefozopran [ATC Code]
- cefozopran [MeSH concept]
Validated automatic mappings to BTNT
- cefozopran [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Cefozopran Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Cefozopran Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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