Preferred Label : Cefdaloxime;
NCIt definition : A third-generation cephalosporin with antibacterial activity. Cefdaloxime binds to
and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of
the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling
the bacterial cell wall and in reshaping the cell wall during growth and division.
Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary
for bacterial cell wall strength and rigidity. This results in the weakening of the
bacterial cell wall and causes cell lysis.;
UNII : 6856HDT30F;
InChIKey : HOGISBSFFHDTRM-GHXIOONMSA-N;
CAS number : 80195-36-4;
Chemical formula : C14H15N5O6S2;
Origin ID : C76161;
UMLS CUI : C2699135;
Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
