NCIt definition : A bisquaternary ammonium alcohol with parasympathomimetic activity. The positive charge
of ambenonium allows it to act as an acetylcholinesterase inhibitor by binding to
the anionic site at the reactive center of acetylcholinesterase, preventing the breakdown
of acetylcholine and producing an indirect cholinomimetic effect at both nicotinic
and muscarinic receptors. Ambenonium also has direct agonist activity at nicotinic
receptors, potentiating the cholinomimetic effect at the neuromuscular junction.;