Enalaprilat Anhydrous

Preferred Label : Enalaprilat Anhydrous;

NCIt definition : The anhydrous form of enalaprilat, a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : Q508Q118JM;

InChIKey : LZFZMUMEGBBDTC-QEJZJMRPSA-N;

CAS number : 76420-72-9;

Chemical formula : C18H24N2O5;

ChEBI ID : CHEBI:4786;

Details

Origin ID

C76135;

UMLS CUI

C0886809;

Automatic exact mappings (from CISMeF team)
- enalaprilat [MeSH Descriptor]
Currated CISMeF NLP mapping
- enalaprilat anhydrous [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- enalaprilat anhydrous [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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