NCIt definition : The anhydrous form of cefaclor, a beta-lactam, second-generation cephalosporin with
antibacterial activity. Cefaclor binds to and inactivates penicillin-binding proteins
(PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs
interferes with the cross-linkage of peptidoglycan chains necessary for bacterial
cell wall strength and rigidity. This results in the weakening of the bacterial cell
wall and causes cell lysis.;