Eflucimibe - CISMeF

Preferred Label : Eflucimibe;

NCIt definition : A dodecylthio-phenylacetanilide derivative with hypocholesterolemic and anti-atherosclerotic properties. Eflucimibe is an inhibitor of acyl-Coenzyme A:cholesterol acyltransferase (ACAT), an intracellular enzyme which catalyzes the esterification of cholesterol into cholesteryl esters and is believed to be involved in intestinal cholesterol absorption, lipoprotein assembly in the liver, steroid hormone production in the adrenal cortex, and foam cell formation in atherosclerotic lesions.;

UNII : 3DK1X2C37M;

InChIKey : ZXEIEKDGPVTZLD-NDEPHWFRSA-N;

CAS number : 202340-45-2;

Chemical formula : C29H43NO2S;

Détails

Origin ID

C75995;

UMLS CUI

C0963171;

Currated CISMeF NLP mapping
- eflucimibe [MeSH concept]
- eflucimibe [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- eflucimibe [MeSH Supplementary Concept]
- eflucimibe [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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