Ambruticin - CISMeF

Preferred Label : Ambruticin;

NCIt definition : A natural polyketide isolated from the myxobacteria Sorangium cellulosum with antifungal activity. Ambruticin interferes with the osmoregulatory system by activating fungal high osmolarity glycerol (HOG) pathway. This results in an accumulation of intracellular glycerol, which in turn causes water influx and swelling of the cell. This ultimately leads to cellular leakage and cell death.;

UNII : X794618736;

InChIKey : TYIXBSJXUFTELJ-LQJOTGEPSA-N;

CAS number : 58857-02-6;

Chemical formula : C28H42O6;

Details

Origin ID

C75987;

UMLS CUI

C0051555;

Currated CISMeF NLP mapping
- ambruticin [MeSH concept]
- ambruticin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ambruticin [MeSH concept]
- ambruticin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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