Ingliforib - CISMeF

Preferred Label : Ingliforib;

NCIt definition : A glycogen phosphorylase inhibitor with antihyperglycemic and cardioprotective activities. Ingliforib inhibits glycogen phosphorylase, the rate-limiting enzyme in glycogenolysis, thereby preventing the release of glucose-1 phosphate from a glycogen molecule in liver. This agent also inhibits glycogen phosphorylase in cardiac muscle and may protect the heart from myocardial ischemic injury by preserving glycogen content and improving glycolytic-oxidative coupling.;

UNII : UII7156WLU;

InChIKey : GVDRRZOORHCTAN-MJUUVYJYSA-N;

CAS number : 186392-65-4;

Chemical formula : C23H24ClN3O5;

Details

Origin ID

C75982;

UMLS CUI

C1436456;

Currated CISMeF NLP mapping
- ingliforib [MeSH concept]
- ingliforib [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ingliforib [MeSH concept]
- ingliforib [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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