Amustaline - CISMeF

Preferred Label : Amustaline;

NCIt synonyms : (N,N-bis(2-chloroethyl))-2-aminoethyl-3-((acridin-9-yl)amino)propionate;

NCIt definition : A quinacrine mustard compound with potential antineoplastic activity. Amustaline binds to, intercalates and crosslinks DNA and RNA. This agent is mainly used for ex vivo purposes, specifically for the inactivation of pathogens such as viruses, protozoa and bacteria in red blood cells (RBCs).;

UNII : 25571657UW;

InChIKey : BDLWRIAFNYVGTC-UHFFFAOYSA-N;

CAS number : 220180-88-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 220180-88-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : S-303;

Chemical formula : C22H25Cl2N3O2;

Details

Origin ID

C75926;

UMLS CUI

C1667749;

Automatic exact mappings (from CISMeF team)
- (N,N-bis(2-chloroethyl))-2-aminoethyl-3-((acridin-9-yl)amino)propionate [MeSH concept]
- (N,N-bis(2-chloroethyl))-2-aminoethyl-3-((acridin-9-yl)amino)propionate [MeSH Supplementary Concept]
CISMeF manual mappings
- amustaline [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- (N,N-bis(2-chloroethyl))-2-aminoethyl-3-((acridin-9-yl)amino)propionate [MeSH Supplementary Concept]
- (N,N-bis(2-chloroethyl))-2-aminoethyl-3-((acridin-9-yl)amino)propionate [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Amustaline Dihydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Amustaline Dihydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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