NCIt definition : A usually autosomal dominant and less frequently autosomal recessive genetic disorder
characterized by the presence of numerous cysts in the kidneys leading to end-stage
renal failure. The autosomal dominant trait is associated with abnormalities on the
short arm of chromosome 16. Symptoms in patients with the autosomal dominant trait
usually appear at middle age and include abdominal pain, hematuria, and high blood
pressure. Patients may develop brain aneurysms and liver cysts. Patients with the
autosomal recessive trait present with progressive renal failure early in life and
symptoms resulting from hepatic fibrosis. The autosomal recessive trait is associated
with abnormalities of chromosome 6. Polycystic kidney disease may also result as a
side effect in patients on renal dialysis.;
Alternative definition : NICHD: An inherited form of kidney disease characterized by multiple renal cysts.;