Avasimibe - CISMeF

Preferred Label : Avasimibe;

NCIt definition : An orally bioavailable inhibitor of acyl-Coenzyme A:cholesterol acyltransferase (ACAT) that prevents cholesterol deposition in the arterial wall. Research was discontinued due to difficulties in assaying the effects of avasimibe on preventing plaque formation and due to its ability to increase the activity of Cytochrome P450 3A4, thus increasing the removal of other drugs from the body.;

UNII : 28LQ20T5RC;

InChIKey : PTQXTEKSNBVPQJ-UHFFFAOYSA-N;

CAS number : 166518-60-1;

Chemical formula : C29H43NO4S;

Details

Origin ID

C75252;

UMLS CUI

C0965226;

Currated CISMeF NLP mapping
- avasimibe [MeSH concept]
- avasimibe [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- avasimibe [MeSH concept]
- avasimibe [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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